Relevance of systems pharmacology in drug discovery

Cucurull-Sanchez, Lourdes and Spink, Karen G. and Moschos, Sterghios A. (2012) Relevance of systems pharmacology in drug discovery. Drug Discovery Today, 17 (13-14). pp. 665-670. ISSN 1359-6446

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The pharmaceutical industry is in the process of re-inventing its pipeline in an attempt to overcome its increasing phase II and III attrition rates. Here, we describe how systems pharmacology can be used as a risk assessment tool to alleviate this problem before bringing in larger investments. We propose that this translational research tool could provide a valuable, complementary addition to other emerging innovative approaches for target identification and validation in discovery and, ultimately, for aiding clinical trial optimization.

Item Type: Article
Subjects: University of Westminster > Science and Technology > Life Sciences, School of (No longer in use)
Depositing User: Miss Nina Watts
Date Deposited: 09 Mar 2012 12:38
Last Modified: 05 Jul 2012 10:55

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