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Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells

Baou, Maria and Jewell, Andrew P. and Muthurania, A. and Wickremasinghe, R.G. and Yong, K.L. and Carr, R. and Marsh, P. and Murphy, John J. (2009) Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells. Leukemia, 23 (5). pp. 986-989. ISSN 0887-6924

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Official URL: http://dx.doi.org/10.1038/leu.2008.340

Abstract

B-cell chronic lymphocytic leukemia is the commonest form of leukemia in the Western world, characterized by an accumulation of monoclonal CD5+ B cells in the peripheral blood and lymphoid organs. It is clinically a heterogenous disease with overall variable response to many drugs used either alone or in combination, and is currently untreatable.

Item Type:Article
Research Community:University of Westminster > Life Sciences, School of
ID Code:11202
Deposited On:17 Oct 2012 11:25
Last Modified:11 Jun 2013 11:51

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