Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study

Taylor-Robinson, Simon D., Thomas, E. Louise, Sargentoni, Janet, Marcus, Claude D., Davidson, Brian R. and Bell, Jimmy D. (1995) Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1272 (2). pp. 113-118. ISSN 0925-4439

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Official URL: http://dx.doi.org/10.1016/0925-4439(95)00074-E

Abstract

Human livers with histologically proven cirrhosis were assessed using in vitro 31P NMR spectroscopy. Spectra were compared with those from histologically normal livers and showed significant elevations in phosphoethanolamine (PE) and phosphocholine (PC) and significant reductions in glycerophosphorylethanolamine (GPE) and glycerophosphorylcholine (GPC). There were no significant differences in spectra from livers with compensated and decompensated cirrhosis. These results help to characterise the alterations in membrane metabolism in cirrhosis of the liver.

Item Type: Article
Subjects: University of Westminster > Science and Technology > Life Sciences, School of (No longer in use)
Depositing User: Miss Nina Watts
Date Deposited: 21 Aug 2014 11:20
Last Modified: 21 Aug 2014 11:20
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/14161

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