Colonic bacterial metabolites and host health

Russell, W., Hoyles, L., Flint, H. J. and Dumas, M.-E. (2013) Colonic bacterial metabolites and host health. Current Opinion in Microbiology, 16 (3). pp. 246-254.

Full text not available from this repository.
Official URL: https://dx.doi.org/10.1016/j.mib.2013.07.002

Abstract

The influence of the microbial-mammalian metabolic axis is becoming increasingly important for human health. Bacterial fermentation of carbohydrates (CHOs) and proteins produces short-chain fatty acids (SCFA) and a range of other metabolites including those from aromatic amino acid (AAA) fermentation. SCFA influence host health as energy sources and via multiple signalling mechanisms. Bacterial transformation of fibre-related phytochemicals is associated with a reduced incidence of several chronic diseases. The 'gut-liver axis' is an emerging area of study. Microbial deconjugation of xenobiotics and release of aromatic moieties into the colon can have a wide range of physiological consequences. In addition, the role of the gut microbiota in choline deficiency in non-alcoholic fatty liver disease (NAFLD) and insulin resistance is receiving increased attention.

Item Type: Article
Subjects: University of Westminster > Science and Technology
SWORD Depositor: repository@westminster.ac.uk
Depositing User: repository@westminster.ac.uk
Date Deposited: 19 Jun 2015 10:22
Last Modified: 23 Feb 2016 16:07
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/15276

Actions (login required)

Edit Item (Repository staff only) Edit Item (Repository staff only)