Relationship between post-awakening salivary cortisol and melatonin secretion in healthy participants

Ramachandran, N., Smyth, N., Thorn, L., Eardley, A.F., Evans, P. and Clow, A. (2016) Relationship between post-awakening salivary cortisol and melatonin secretion in healthy participants. Stress, 19 (2). pp. 260-263. ISSN 1025-3890

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Official URL: https://dx.doi.org/10.3109/10253890.2016.1146671

Abstract

We report the relationship between patterns of post-awakening salivary melatonin and cortisol secretion in healthy participants (n=51; mean age 21.6 ±5.0 years). Saliva samples were collected within the domestic setting, at 0-, 15-, 30-, and 45-min post-awakening on 2 consecutive typical weekdays. Analyses were undertaken on data with electronically verified sample timing accuracy (55-min delay between awakening and the start of saliva sampling). Melatonin secretion declined linearly by an average of 29% within the first 45-min post-awakening. In contrast, there was a marked 112% surge in cortisol, characteristic of the cortisol awakening response. No day differences in melatonin or cortisol secretion were observed but melatonin concentrations were lower with later awakening. Despite contrasting post-awakening changes in these hormones, there was a lack of relationship between overall levels or patterns of melatonin and cortisol during this period.

Item Type: Article
Additional Information: BIAL Foundation grant number 72/12
Uncontrolled Keywords: Saliva, CAR, awakening, circadian, biological dawn, diurnal;
Subjects: University of Westminster > Science and Technology
SWORD Depositor: repository@westminster.ac.uk
Depositing User: repository@westminster.ac.uk
Date Deposited: 30 Mar 2016 09:42
Last Modified: 03 Mar 2017 23:02
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/16792

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