Exercise increases the dynamics of diurnal cortisol secretion and executive functionin people wiht MCI.

Tortosa-Martínez, J., Clow, A., Caus-Pertegaz, N., González-Caballero, G., Abellán-Miralles, I. and Saenz, M.J. (2015) Exercise increases the dynamics of diurnal cortisol secretion and executive functionin people wiht MCI. Journal of Aging and Physical Activity, 23 (4). pp. 550-558. ISSN 1063-8652

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Official URL: https://dx.doi.org/10.1123/japa.2014-0006

Abstract

Summary: Regular physical activity is protective against and beneficial for Mild Cognitive Impairment (MCI), dementia, and Alzheimer´s disease. The mechanisms underlying these benefits remain unknown although it has been suggested that exercise-induced changes in the circadian pattern of cortisol secretion may be implicated. Fitness, salivary cortisol levels (0 and 30 mins post awakening, midday, 5pm and 9pm) and cognitive function were determined in a group of amnestic MCI patients (n=39) before and after a three-month exercise program (n=19) or usual care (n=20). At base fitness measures were positively correlated with peak levels of cortisol and a greater fall in cortisol concentration from peak levels to midday. The exercise intervention successfully increased fitness and resulted in a greater fall in cortisol concentration from peak to midday, compared to the control group. The exercise intervention enhanced indices of executive function, although memory, mood, and functionality were not affected.

Item Type: Article
Uncontrolled Keywords: Mild cognitive impairment, Alzheimer´s disease, exercise, cortisol, stress;
Subjects: University of Westminster > Science and Technology
SWORD Depositor: repository@westminster.ac.uk
Depositing User: repository@westminster.ac.uk
Date Deposited: 11 Jan 2017 15:06
Last Modified: 11 Jan 2017 15:06
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/18181

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