A portable instrument for measuring macular pigment with central fixation

Mellerio, John, Ahmadi-Lari, S., van Kuijk, F.J.G.M., Pauleikhoff, D., Bird, A.C. and Marshall, J. (2002) A portable instrument for measuring macular pigment with central fixation. Current Eye Research, 25 (1). pp. 37-47. ISSN 0271-3683


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urpose: To evaluate the reliability and validity of a portable instrument for measuring macular pigment optical density. Methods: The instrument is small, uses light emitting diodes as light sources and the principles of heterochromatic flicker photometry of comparing foveal and extra-foveal minimum flicker matches. It uses central fixation for the extra-foveal matches, which subjects found easier than eccentric fixation. Subjects with healthy eyes used the instrument to measure their pigment density in a number of eye clinics. Results: The mean pigment density in 124 eyes in 124 individuals was 0.41 +/- 0.16 (mean +/- sd), there was no significant change with age but the density was less in females, those with light irides, smokers, subjects on diets low in precursor carotenoids and in those exposed to several hours of daylight every day or who used sun beds. Conclusions: The portable instrument gave valid and reliable data that confirmed published values for macular pigment. It was convenient to use in the clinic and has potential as a screening tool.

Item Type: Article
Uncontrolled Keywords: Macular pigment, screening; smoking, light exposure, age-related macular degeneration
Subjects: University of Westminster > Science and Technology > Life Sciences, School of (No longer in use)
Depositing User: Users 4 not found.
Date Deposited: 01 Dec 2005
Last Modified: 11 Aug 2010 14:29
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/328

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