Executive functions are impaired in patients with Parkinson's disease with visual hallucinations

Barnes, James and Boubert, Laura (2008) Executive functions are impaired in patients with Parkinson's disease with visual hallucinations. Journal of Neurology, Neurosurgery and Psychiatry, 79 (2). pp. 190-192. ISSN 0022-3050

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Official URL: http://dx.doi.org/10.1136/jnnp.2007.116202


Objectives: Although cognitive impairment has been identified as a risk factor for visual hallucinations (VHs), more specific neuropsychological deficits underlying such phenomena have not been established. Here, we investigate the link between executive dysfunction and the occurrence of VHs. Methods: We evaluated three groups—17 patients with Parkinson’s disease (PD) with VHs, 20 patients with PD without VHs and 20 age-matched controls—on a battery of tests previously reported to evaluate executive functions, namely tests of inhibitory ability, short-term memory and working memory. Results: Differences were found on tests of inhibitory ability, for which the patient group with VHs showed impairment when compared with the non-hallucinating group. Conclusions: Patients with PD with VHs have substantially greater impairment of inhibitory ability than patients without VHs. These findings support interactive models of the genesis of visual hallucinations in PD.

Item Type: Article
Subjects: University of Westminster > Social Sciences and Humanities
Depositing User: Miss Nina Watts
Date Deposited: 30 Apr 2009 11:45
Last Modified: 30 Apr 2009 11:45
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/6705

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