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Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications

Misra, Superb K. and Ohashi, F. and Valappil, Sabeel P. and Knowles, Jonathan C. and Roy, Ipsita and Ravi , S. and Silva, P. and Salih, Vehid and Boccaccini, Aldo R. (2010) Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications. Acta Biomaterialia, 6 (3). pp. 735-742. ISSN 1742-7061

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Official URL: http://dx.doi.org/10.1016/j.actbio.2009.09.023

Abstract

Poly(3-hydroxybutyrate) (P(3HB)) composites with bioactive glass particles and multiwall carbon nanotubes (MWCNTs) were prepared and used to identify whether the electrical properties of MWCNTs can be used to detect the bioactivity of P(3HB)/bioactive glass composites. The presence of MWCNTs (2–7 wt.%) increased the surface roughness of the composites. The presence of MWCNTs in low quantity enhanced MG-63 osteoblast-like cell attachment and proliferation compared to composites with higher concentration of MWCNTs. Current–voltage measurements demonstrated that the electrical resistance of the composites containing bioactive glass particles decreased over a 45-day immersion period in SBF, whereas composites without bioactive glass showed no significant change over the same period.

Item Type:Article
Research Community:University of Westminster > Life Sciences, School of
ID Code:7113
Deposited On:06 Jan 2010 12:51
Last Modified:11 Mar 2010 15:54

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