Exploring the role of glycosylated hemoglobin as a marker for type 2 diabetes mellitus using rough sets

Revett, Kenneth and Salem, Abdel-Badeeh M. (2010) Exploring the role of glycosylated hemoglobin as a marker for type 2 diabetes mellitus using rough sets. In: The 7th International Conference on Informatics and Systems (INFOS). IEEE, pp. 1-7. ISBN 9781424458288

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This study investigated the role of glycosylated hemoglobin (HbAlc) levels as a predictor of type 2 diabetes mellitus (T2DM). A dataset containing clinical data from 403 patients was investigated using the rough sets approach. The dataset contained a range of physiological features typically associated with diagnosing diabetes, including gylcosylated hemoglobin. It has been reported in many studies that HbAlc has high predictive capacity with respect to T2DM. In order to investigate directly the predictive role of HbAlc, a rough sets approach was used, utilising the classification feature of this machine learning approach. The HbAlc feature was discretised over a range of values (4.0-8.0) and the classification accuracy was established for each level. The first result of this study worth noting is that HbAlc was a significant feature associated with T2DM. Further, the results indicated that HbAlc values in the range of 6.0-7.5 produced the highest classification accuracy. Lastly, we present several rules extracted from this dataset that can provide quantitative rules in human readable form that can be verified clinically.

Item Type: Book Section
Subjects: University of Westminster > Science and Technology > Electronics and Computer Science, School of (No longer in use)
Depositing User: Miss Nina Watts
Date Deposited: 12 Jan 2010 13:07
Last Modified: 26 Mar 2014 15:02
URI: http://westminsterresearch.wmin.ac.uk/id/eprint/7190

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