Green, David A. and Golding, John F. and Mandip, Aulukh and Faldon, Mary C. and Murphy, Kevin G. and Bronstein, Adolfo M. and Gresty, Michael A. (2008) Adaptation of ventilation to 'buffeting' in vehicles. Clinical Autonomic Research, 18 (6). pp. 346-351. ISSN 0959-9851Full text not available from this repository.
Objectives Short exposures to buffeting in a vehicle driving over rough terrain induce an increase in the frequency of respiration resulting in hyperpnoea and hypocapnia. The present study investigates the adaptation to buffeting-induced hyperpnoea. Methods We monitored ventilation and cardiovascular function in nine healthy young adults prior to, throughout and post a 30 minute simulation of buffeting. Results All subjects had a consistent elevation of respiratory frequency throughout motion. End-tidal CO2 decreased during the first 5 minutes of buffeting due to a transient increase in minute ventilation. Elevation of respiratory frequency was facilitated by shortening of inspiration without change in expiratory time. Tidal volume was maintained which resulted in an increase in mean inspiratory flow during buffeting. At later stages of motion there was a partial return to normal for mean inspiratory flow, minute ventilation and end-tidal CO2 because of a slight reduction in tidal volume whilst inspiratory time remained shortened. Salivary cortisol levels were unaffected by motion, suggesting that the hyperpnoea was not secondary to non-specific stress. Interpretation The cause of elevated respiratory frequency during buffeting could be due to mechanical action on the torso, vestibular-respiratory drive or a protective reinforcement of the torso.
|Subjects:||University of Westminster > Social Sciences and Humanities|
|Depositing User:||Miss Nina Watts|
|Date Deposited:||16 Jul 2010 11:19|
|Last Modified:||16 Jul 2010 11:19|
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