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Urinary output of endogenous monoamine oxidase inhibitory activity is related to everyday stress

Doyle, A. and Hucklebridge, Frank and Evans, Philip D. and Clow, Angela (1996) Urinary output of endogenous monoamine oxidase inhibitory activity is related to everyday stress. Life Sciences, 58 (20). pp. 1723-1730. ISSN 0024-3205

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Official URL: http://dx.doi.org/10.1016/0024-3205(96)00153-1

Abstract

The MAO A and B inhibitory components of urinary tribulin were investigated in normal individuals (11 males and 24 females, mean age ± SD: 27.1 ± 4.5 years) in relation to everyday stress. Volunteers collected a urine sample at the same time (late evening) on five days over a single week. On each occasion subjects also completed a mood adjective checklist which measured perceived stress levels over the day in question. For each subject all daily measures were aggregated. Mean individual urinary MAO A and B inhibitory activity was found to be positively correlated with stress scores both before (r = 0.38, p < 0.05 and r = 0.37, p < 0.05 respectively, n = 35) and after (r = 0.35, p < 0.05 and r = 0.33, p < 0.05 respectively, n = 35) correction for the effects of urinary volume. These results suggest that in normal healthy individuals high endogenous MAO inhibitory activity in the urine is indicative of a relatively enduring state of everyday stress.

Item Type:Article
Research Community:University of Westminster > Social Sciences, Humanities and Languages, School of
ID Code:9945
Deposited On:07 Dec 2011 11:59
Last Modified:07 Dec 2011 11:59

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