Clow, Angela, Freestone, Clare, Lewis, Emma, Dexter, David, Sandler, Merton and Glover, Vivette (1993) The effect of pergolide and MDL 72974 on rat brain CuZn superoxide dismutase. Neuroscience Letters, 164 (1-2). pp. 41-43. ISSN 0304-3940Full text not available from this repository.
It has previously been shown that both the dopamine receptor agonist, pergolide, and the monoamine oxidase inhibitor. (?)-deprenyl, can cause induction of CuZn superoxide dismutase in the rat striatum. We have now confirmed this effect of pergolide (0.04 mg/kg i.p.) as being localised to the striatum, but not the cerebellum, and shown it to take 3 weeks to develop. Furthermore, we have found that MDL 72974, a more specific monoamine oxidase inhibitor than (?)-deprenyl, failed to bring about such an induction either at a low selective monoamine oxidase B inhibitory dose, or at a higher non-selective dose.
|Subjects:||University of Westminster > Social Sciences and Humanities|
|Depositing User:||Rachel Wheelhouse|
|Date Deposited:||07 Dec 2011 11:57|
|Last Modified:||07 Dec 2011 11:57|
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