Isatin, regional distribution in rat brain and tissues

Watkins, P. and Clow, Angela and Halket, J. and Przyborowska, A. and Sandler, M. (1990) Isatin, regional distribution in rat brain and tissues. Neurochemistry International, 17 (2). pp. 321-323. ISSN 0197-0186

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Isatin has recently been identified in rat tissues and normal human urine, where it forms the major proportion of the endogenous monoamine oxidase inhibitor, tribulin. In this paper, we show that isatin, measured by gas chromatography/mass spectrometry, has a distinct regional distribution in rat tissues, with highest concentrations in seminal vesicles (1.6 ?g/g) and vas deferens (3.4 ?g/g). There was also a discontinuous distribution within rat brain, concentrations being highest in the hippocampus (0.13 ?g/g).

Item Type: Article
Subjects: University of Westminster > Social Sciences and Humanities
Depositing User: Rachel Wheelhouse
Date Deposited: 07 Dec 2011 11:54
Last Modified: 07 Dec 2011 11:54

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