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Tribulin in post-traumatic stress disorder

Davidson, J. and Glover, Vivette and Clow, Angela and Kudler, H. and Meador, K. and Sandler, M. (1988) Tribulin in post-traumatic stress disorder. Psychological Medicine, 18 (4). pp. 833-836. ISSN 0033-2917

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Official URL: http://dx.doi.org/10.1017/S0033291700009764

Abstract

Tribulin (endogenous monoamine oxidase inhibitor/benzodiazepine receptor binding inhibitor) output was measured in the urine of 18 patients with post-traumatic stress disorder (PTSD) and 13 controls. The level of the two inhibitory activities was highly significantly correlated in the group as a whole. There was no difference between output of either inhibitor in patients and controls. However, when the PTSD group was subdivided according to various psychometric ratings, a pattern of output did emerge. Levels of both inhibitory activities were higher in agitated compared with non-agitated subjects, and lower in extroverts compared with introverts. This finding supports the view that tribulin output is raised in conditions of greater arousal.

Item Type:Article
Research Community:University of Westminster > Social Sciences, Humanities and Languages, School of
ID Code:9967
Deposited On:07 Dec 2011 11:50
Last Modified:07 Dec 2011 11:50

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