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Items where Author is Abraham, David J.

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Number of items: 13.

Shi-Wen, Xu and Chen, Yunliang and Denton, Christopher P. and Eastwood, Mark and Renzoni, Elisabetta A. and Bou-Gharios, George and Pearson, Jeremy and Dashwood, Michael and du Bois, Roland and Black, Carol M. and Leask, Andrew and Abraham, David J. (2004) Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. Molecular Biology of the Cell, 15 (6). pp. 2707-2719. ISSN 1059-1524

Chen, Yunliang and Shi-wen, Xu and van Beek, Jonathan and Kennedy, Laura and McLeod, Marilyn and Renzoni, Elisabetta A. and Bou-Gharios, George and Wilcox-Adelman, Sarah and Goetinck, Paul F. and Eastwood, Mark and Black, Carol M. and Abraham, David J. and Leask, Andrew (2005) Matrix contraction by dermal fibroblasts requires transforming growth Factor-ß /activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease. American Journal of Pathology, 167 (6). pp. 1699-1711. ISSN 0002-9440

Chen, Yunliang and Shi-Wen, Xu and Eastwood, Mark and Black, Carol M. and Denton, Christopher P. and Leask, Andrew and Abraham, David J. (2006) Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts. Arthritis & Rheumatism, 54 (4). pp. 1309-1316. ISSN 0004-3591

Denton, Christopher P. and Lindahl, Gisela E. and Khan, Korsa and Shiwen, Xu and Ong, Voon H. and Gaspar, Nicholas J. and Lazaridis, Konstantinos and Edwards, Dylan R. and Leask, Andrew and Eastwood, Mark and Leoni, Patricia and Renzoni, Elisabetta A. and Bou-Gharios, George and Abraham, David J. and Black, Carol M. (2005) Activation of Key Profibrotic Mechanisms in Transgenic Fibroblasts Expressing Kinase-deficient Type II Transforming Growth Factor beta-receptor (T beta RII delta k). Journal of Biological Chemistry, 280 (16). pp. 16053-16065. ISSN 0021-9258

Chen, Yunliang and Leask, Andrew and Abraham, David J. and Pala , Daphne and Shiwen, Xu and Khan, Korsa and Liu, Shangxi and Carter , David E. and Wilcox-Adelman , Sarah and Goetinck, Paul F. and Denton, Christopher P. and Black , Carol M. and Pitsillides, Andrew A. and Sarraf, Catherine and Eastwood, Mark (2008) Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts. Arthritis & Rheumatism, 58 (2). pp. 577-585. ISSN 0004-3591

Shangxi, Liu and Shi-Wen, Xu and Kennedy, Laura and Pala, Daphne and Chen, Yunliang and Eastwood, Mark and Carter, David E. and Black, Carol M. and Abraham, David J. and Leask, Andrew (2007) FAK Is Required for TGFβ-induced JNK Phosphorylation in Fibroblasts: Implications for Acquisition of a Matrix-remodeling Phenotype. Molecular Biology of the Cell, 18 (6). pp. 2169-2178. ISSN 1059-1524

Kennedy, Laura and Liu, Shangxi and Shi-wen, Xu and Chen, Yunliang and Eastwood, Mark and Carter, David E. and Lyon, Karen M. and Black, Carol M. and Abraham, David J. and Leask, Andrew (2007) CCN2 is necessary for the function of mouse embryonic fibroblasts. Experimental Cell Research, 313 (5). pp. 952-964. ISSN 0014-4827

Shi-wen, Xu and Eastwood, Mark and Stratton, Richard J. and Denton, Christopher P. and Leask, Andrew and Abraham, David J. (2010) Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts. Rheumatology, 49 (2). pp. 259-263. ISSN 1462-0324

Denton, Christopher P. and Khan, Korsa and Hoyles, Rachel K. and Shiwen, Xu and Leoni, Patricia and Chen, Yunliang and Eastwood, Mark and Abraham, David J. (2009) Inducible lineage-specific deletion of TβRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing. Journal of Investigative Dermatology, 129 (1). pp. 194-204. ISSN 0022-202X

Shi-Wen , Xu and Parapuram, Sunil K. and Pala , Daphne and Chen, Yunliang and Carter , David E. and Eastwood, Mark and Denton, Christopher P. and Abraham, David J. and Leask, Andrew (2009) Requirement of transforming growth factor β–activated kinase 1 for transforming growth factor β–induced -smooth muscle actin expression and extracellular matrix contraction in fibroblasts. Arthritis & Rheumatism, 60 (1). pp. 234-241. ISSN 0004-3591

Chen, Yunliang and Leask, Andrew and Abraham, David J. and Kennedy, Laura and Shi-Wen , Xu and Denton, Christopher P. and Black , Carol M. and Verjee, Liaquat Suleman and Eastwood, Mark (2011) Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism. Fibrogenesis and tissue repair, 4 (9). ISSN 1755-1536

Liu, Shangxi and Shi-Wen , Xu and Blumbach, Katrin and Eastwood, Mark and Denton, Christopher P. and Eckes, Beate and Krieg, Thomas and Abraham, David J. and Leask, Andrew (2010) Expression of integrin β1 by fibroblasts is required for tissue repair in vivo. Journal of Cell Science, 123 (21). pp. 3674-3682. ISSN 0021-9533

Shi-Wen , Xu and Liu, Shangxi and Eastwood, Mark and Sonnylal, Sonali and Denton, Christopher P. and Abraham, David J. and Leask, Andrew (2009) Rac inhibition reverses the phenotype of fibrotic fibroblasts. PLoS ONE, 4 (10). e7438. ISSN 1932-6203

This list was generated on Fri Jul 25 05:48:57 2014 BST.