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Items where Author is Barr, Alastair J.

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Number of items: 25.

2013

Shintre, Chitra A. and Pike, Ashley C. W. and Li, Qiuhong and Kim, Jung-In and Barr, Alastair J. and Goubin, Solenne and Shrestha, Leela and Yang, Jing and Berridge, Georgina and Ross, Jonathan and Stansfeld, Phillip J. and Sansom, Mark S. P. and Edwards, Aled M. and Bountra, Chas and Marsden, Brian and von Delft, Frank and Bullock, Alex N. and Gileadi, Opher and Burgess-Brown, Nicola A. and Carpenter, Elisabeth P. (2013) Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states. Proceedings of the National Academy of Sciences, 110 (24). pp. 9710-9715. ISSN 0027-8424

2011

Hashemia, Hamid and Hurley, Michael and Gibson, Anna and Panova, Veera and Tchetchelnitski, Viktoria and Barr, Alastair J. and Stoker, Andrew W. (2011) Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis. Molecular and Cellular Neuroscience, 46 (2). pp. 469-482. ISSN 1044-7431

Salah, Eidarus and Ugochukwu, Emilie and Barr, Alastair J. and von Delft, Frank and Knapp, Stefan and Elkins, Jonathan M. (2011) Crystal structures of ABL-related gene (ABL2) in complex with imatinib, tozasertib (VX-680), and a type I inhibitor of the triazole carbothioamide class. Journal of Medicinal Chemistry, 54 (7). pp. 2359-2367. ISSN 0022-2623

2010

Barr, Alastair J. (2010) Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development. Future Medicinal Chemistry, 2 (10). pp. 1563-1576. ISSN 1756-8919

Ellison, S. and Mori, J. and Barr, Alastair J. and Senis, Y.A. (2010) CD148 enhances platelet responsiveness to collagen by maintaining a pool of active Src family kinases. Journal of Thrombosis and Haemostasis, 8 (7). pp. 1575-1583. ISSN 1538-7933

2009

Barr, Alastair J. and Knapp, Stefan (2009) Large scale structural analysis of protein tyrosine phosphatases. In: Bradshaw, Ralph and Dennis, Edward, (eds.) Handbook of cell signaling (2nd edition). Elsevier, San Diego, CA, pp. 871-876. ISBN 9780123741455

Barr, Alastair J. and Ugochukwu, Emilie and Lee, Wen Hwa and King, Oliver N.F. and Filippakopoulos, Panagis and Alfano, Ivan and Savitsky, Pavel and Burgess-Brown, Nicola A. and Muller, Susanne and Knapp, Stefan (2009) Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell, 136 (2). pp. 352-363. ISSN 0092-8674

Gingras, Marie-Claude and Zhang, Yu Ling and Kharitidi, Dmitri and Barr, Alastair J. and Knapp, Stefan and Tremblay, Michel L. and Pause, Arnim (2009) HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain. PLoS ONE, Online . ISSN 1932-6203

2008

Jeeves, Mark and McClelland, Darren M. and Barr, Alastair J. and Overduin, Michael (2008) Sequence-specific 1H, 13C and 15N backbone resonance assignments of the 34 kDa catalytic domain of human PTPN7. Biomolecular NMR Assignments, 2 (2). pp. 101-103. ISSN 1874-2718

2006

Barr, Alastair J. and Debreczeni, Judit E. and Eswaran, Jeyanthy and Knapp, Stefan (2006) Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution. Proteins, 63 (4). pp. 1132-1136. ISSN 0887-3585

Barr, Alastair J. and Knapp, Stefan (2006) MAPK-specific tyrosine phosphatases: new targets for drug discovery? Trends in Pharmacological Sciences, 27 (10). pp. 525-530. ISSN 0165-6147

Eswaran, Jeyanthy and Debreczeni, Judit E. and Longman, Emma and Barr, Alastair J. and Knapp, Stefan (2006) The crystal structure of human receptor protein tyrosine phosphatase κ phosphatase domain 1. Protein Science, 15 (6). pp. 1500-1505. ISSN 0961-8368

Eswaran, Jeyanthy and von Kries, Jens Peter and Marsden, Brian and Longman, Emma and Debreczeni, Judit E. and Ugochukwu, Emilie and Turnbull, Andrew and Lee, Wen Hwa and Knapp, Stefan and Barr, Alastair J. (2006) Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochemical Journal, 395 (3). pp. 483-491. ISSN 0264-6021

2002

Barr, Alastair J. and Marjoram, Robin J. and Xu, Jing and Snyderman, Ralph (2002) Phospholipase C-β 2 interacts with mitogen-activated protein kinase kinase 3. Biochemical and Biophysical Research Communications, 293 (1). pp. 647-652. ISSN 0006-291X

2001

Richardson, Ricardo M. and Marjoram, Robin J. and Barr, Alastair J. and Snyderman, Ralph (2001) RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses. Biochemistry, 40 (12). pp. 3583-3588. ISSN 0006-2960

2000

Barr, Alastair J. and Ali, Hydar and Haribabu, Bodduluri and Snyderman, Ralph and Smrcka, Alan V. (2000) Identification of a region at the N-terminus of phospholipase C-beta 3 that interacts with G protein beta gamma subunits. Biochemistry, 39 (7). pp. 1800-1806. ISSN 0006-2960

Haribabu, Bodduluri and Richardson, Ricardo M. and Verghese, Margrith W. and Barr, Alastair J. and Zhelev , Doncho V. and Snyderman, Ralph (2000) Function and regulation of chemoattractant receptors. Immunologic Research, 22 (2-3). pp. 271-279. ISSN 0257-277X

1999

Barr, Alastair J. and Manning, David R. (1999) Agonist-promoted GTP[S35]-binding as a probe for receptor.G protein communication in Sf9 cells. In: Manning, David R., (ed.) G proteins: techniques of analysis. CRC Press, Boca Raton, FL, pp. 227-246. ISBN 9780849333811

Windh, Rolf T. and Lee, Menq-Jer and Hla, Timothy and An, Songzhu and Barr, Alastair J. and Manning, David R. (1999) Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the Gi, Gq, and G12 families of heterotrimeric G proteins. Journal of Biological Chemistry, 274 (39). pp. 27351-27358. ISSN 0021-9258

1998

Ali, Hydar and Sozzani, Silvano and Fisher, Ian and Barr, Alastair J. and Richardson, Ricardo M. and Haribabu, Bodduluri and Snyderman, Ralph (1998) Differential regulation of formyl peptide and platelet-activating factor receptors: role of phospholipase Cbeta3 phosphorylation by protein kinase A. Journal of Biological Chemistry, 273 (18). pp. 11012-11016. ISSN 0021-9258

1997

Barr, Alastair J. and Brass, Lawrence F. and Manning, David R. (1997) Reconstitution of receptors and GTP-binding regulatory proteins (G Proteins) in Sf9 Cells: a direct evaluation of selectivity in receptor.G protein coupling. Journal of Biological Chemistry, 272 (4). pp. 2223-2229. ISSN 0021-9258

Barr, Alastair J. and Manning, David R. (1997) Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in spodoptera frugiperda cells: distinguishing inverse agonists from neutral antagonists. Journal of Biological Chemistry, 272 (52). pp. 32979-32987. ISSN 0021-9258

1994

Barr, Alastair J. and Watson, Steve P. (1994) Protein kinase C mediates delayed inhibitory feedback regulation of human neurokinin type 1 receptor activation of phospholipase C in UC11 astrocytoma cells. Molecular Pharmacology, 46 (2). pp. 266-273. ISSN 0026-895X

1993

Barr, Alastair J. and Watson, Steve P. (1993) Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors. British Journal of Pharmacology, 108 (1). pp. 223-227. ISSN 0007-1188

1991

Barr, Alastair J. and Watson, Steve P. and Bernal, Andres Lopez and Nimmo, Alan J. (1991) The presence of NK3 tachykinin receptors on rat uterus. European Journal of Pharmacology, 203 (2). pp. 287-290. ISSN 0014-2999

This list was generated on Sun Aug 31 09:55:37 2014 BST.