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Number of items: 48.

Article

Basnett, Pooja, Ching, K.Y., Stolz, M., Knowles, Jonathan C., Boccaccini, Aldo R., Smith, Caroline L., Locke, Ian C., Keshavarz, Tajalli and Roy, Ipsita (2013) Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications. Reactive and Functional Polymers, 73 (10). pp. 1340-1348. ISSN 1381-5148

Basnett, Pooja, Ching, K.Y., Stolz, M., Knowles, Jonathan C., Boccaccini, Aldo R., Smith, Caroline L., Locke, Ian C. and Roy, Ipsita (2013) Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents. Bioinspired, Biomimetic and Nanobiomaterials, 2 (3). pp. 141-153. ISSN 2045-9858

Intekhab Alam, Nabila Yasmin, White, Omeco Bianco, Getting, Stephen J., Petsa, A., Knight, Richard A., Townsend, Paul A., Lawrence, Kevin M. and Locke, Ian C. (2013) Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis? Cell Death and Disease, 4. e717. ISSN 2041-4889
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Combs, Charlotte, Fuller, Karen, Kumar, Hashethra, Albert, Anthony P., Pirianov, Grisha, McCormick, James, Locke, Ian C., Chambers, Timothy J. and Lawrence, Kevin M. (2012) Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel. Journal of Endocrinology, 212 (2). pp. 187-197. ISSN 0022-0795

Rai, Ranjana, Boccaccini, Aldo R., Knowles, Jonathan C., Mordon, Nicola, Salih, Vehid, Locke, Ian C., Moshrefi-Torbati, M., Keshavarz, Tajalli and Roy, Ipsita (2011) The homopolymer poly(3-hydroxyoctanoate) as a matrix material for soft tissue engineering. Journal of Applied Polymer Science, 122 (6). pp. 3606-3617. ISSN 0021-8995

Francis, Lydia, Meng, Decheng, Locke, Ian C., Mordon, Nicola, Salih, Vehid, Knowles, Jonathan C., Boccaccini, Aldo R. and Roy, Ipsita (2010) The influence of tetracycline loading on the surface morphology and biocompatibility of films made from P(3HB) microspheres. Advanced Engineering Materials, 12 (7). B260-B268. ISSN 1438-1656

Getting, Stephen J., Kaneva, Magdalena, Bhadresa, Y., Renshaw, Derek, Leoni , Giovanna, Patel, H.B., Kerrigan, Mark J.P. and Locke, Ian C. (2009) Melanocortin peptide therapy for the treatment of arthritic pathologies. The Scientific World Journal, 9. pp. 1394-1414. ISSN 1537-744X

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2009) Melanocortin peptides modulate pro-inflammatory mediator release from TNF-a stimulated C-20/A4 cells. pA2 Online. From the Queen Elizabeth II Conference Centre London, Winter 2009 Meeting: Proceedings of the British Pharmacological Society. 126P. ISSN 1741-1157

Abuirmeileh, Amjad , Lever, Rebecca, Kingsbury, Ann E., Lees, Andrew J. , Locke, Ian C., Knight, Richard A., Chowdrey, Hardial S., Biggs, Christopher S. and Whitton, Peter S. (2007) The corticotrophin-releasing factor-like peptide urocortin reverses key deficits in two rodent models of Parkinson's disease. European Journal of Neuroscience, 26 (2). pp. 417-423. ISSN 0953-816X

Shah, Chirag M., Bell, Susannah E., Locke, Ian C., Chowdrey, Hardial S. and Gordge, Michael P. (2007) Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery. Nitric Oxide, 16 (1). pp. 135-142. ISSN 1089-8603
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Prashar, Anjali, Locke, Ian C. and Evans, Christine S. (2006) Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Proliferation, 39 (4). pp. 241-248. ISSN 0960-7722

Biggs, Christopher S., Abuirmeileh, Amjad , Locke, Ian C., Knight, Richard A., Chowdrey, Hardial S. and Whitton, Peter S. (2005) Urocortin attenuates key indicators of nigrostriatal pathway destruction in a rat hemiparkinsonian model. Proceedings of the British Pharmacological Society, 3 (4).

Locke, Ian C. and Carpenter, Brian (2004) Functional characteristics of the streptococcal deoxyribonuclease 'streptodornase', a protein with DNase activity present in the medicament Varidase. Enzyme and Microbial Technology, 35 (1). pp. 67-73. ISSN 0141-0229

Prashar, Anjali, Locke, Ian C. and Evans, Christine S. (2004) Cytotoxicity of lavender oil and its major components to human skin cells. Cell Proliferation, 37 (3). pp. 221-229. ISSN 0960-7722

Shah, Chirag M., Locke, Ian C., Chowdrey, Hardial S. and Gordge, Michael P. (2003) Rapid S-nitrosothiol metabolism by platelets and megakaryocytes. Biochemical Society Transactions, 31 (6). pp. 1450-1452. ISSN 0300-5127

Locke, Ian C. and Carpenter, Brian (2002) Ion-dependency of the streptococcal deoxyribonuclease "streptodornase", an active constituent of the medicament Varidase. Enzyme and Microbial Technology, 31 (4). pp. 482-489. ISSN 0141-0229

Rutter, P.M., Carpenter, B., Hill, S.S. and Locke, Ian C. (2000) Varidase: the science behind the medicament. Journal of Wound Care, 9 (5). pp. 223-226. ISSN 0969-0700

Locke, Ian C., Leaker, B. and Cambridge, G. (1999) A comparison of the characteristics of circulating anti-myeloperoxidase antibodies in vasculitis with those in non-vasculitic conditions. Clinical and Experimental Immunology, 115 (2). pp. 369-376. ISSN 0009-9104

Liu, Yu-Zhen, Lee, Il-Kwon, Locke, Ian C., Dawson, Sally J. and Latchman, David (1998) Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. Nucleic Acids Research, 26 (10). pp. 2464-2472. ISSN 0305-1048

Locke, Ian C., Cox, S.F. and Carpenter, B.G. (1997) Purification of a streptococcal deoxyribonuclease by affinity chromatography based on a DNA-cellulose matrix. Journal of Chromatography A, 788 (1-2). pp. 75-80. ISSN 0021-9673

Locke, Ian C., Worral, J.G., Leaker, B., Black, C.M. and Cambridge, G. (1997) Autoantibodies to myeloperoxidase in systemic sclerosis. Journal of Rheumatology, 24 (1). pp. 86-89. ISSN 0315-162X

Locke, Ian C. and Cambridge, G. (1996) Autoantibodies to neutrophil granule proteins: pathogenic potential in vasculitis? British Journal of Biomedical Science, 53 (4). pp. 302-316. ISSN 0967-4845

Locke, Ian C., Ramsay, M.P., Hill, S.S. and Carpenter, B.G. (1993) Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®. The Journal of Automatic Chemistry, 15. pp. 65-70. ISSN 2090-8865

Book Section

Curras Lino, M., Radman, Romeo, Bertaud, F., Nisula, L., Lenon, G., Holbom, B., Locke, Ian C., Thompson, S. and Keshavarz, Tajalli (2006) Biological activity of industrial wood and bark waste from Pinus nigra. In: Actual problems of creation of new medicinal preparations of natural origin: the 10th international congress PHYTOPHARM 2006, St.-Petersburg, June 27-30, 2006: proceedings of congress. PHYTOPHARM, St Petersburg, Russia, pp. 401-403.

Conference or Workshop Item

Ashioti, Maria, Getting, Stephen J., Locke, Ian C. and Milton, Nathaniel G.N. (2013) Neuroprotective efficacy of the endogenous neuropeptide Urocortin in a oxygen-glucose deprivation model of transient cerebral ischaemia with reperfusion. In: British Neuroscience Association 22nd Biennial Meeting, 7th-10th April 2013, London.

White, O.B, Intekhab-Alam, N.Y., Chowdrey, H.S., Knight, R.A. and Locke, Ian C. (2011) Chondrocyte CRF receptor expression and Urocortin I mediated chondroprotection. In: Rheumatology 2011, 12th-14th April 2011, Brighton, UK.

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2011) MC1 and MC3 activation inhibits caspase-3 production and activity, promotes cell-viability, and induces IL-10 and HO-1 release from human C20/A4 chondrocytes. In: Physiological Society Meeting 23, University of Oxford.

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2011) ?-MSH and [DTRP]8-?-MSH inhibit pro-inflammatory cytokine release from stimulated primary bovine chondrocytes. In: 10th World Congress on Inflammation, 25–29 June 2011, Paris, France.

Rai, Ranjana, Boccaccini, Aldo R., Knowles, Jonathan C., Locke, Ian C., Gordge, Michael P., McCormick, Aine, Salih, Vehid, Mordon, Nicola, Keshavarz, Tajalli and Roy, Ipsita (2010) Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing. In: 5th international conference on times of polymers (TOP) and composites, 20–23 June 2010 , Ischia, Italy.

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2010) The MC3 agonist dTRP8-?-MSH inhibits IL-6 and IL-8 release from TNF-? stimulated C-20/A4 chondrocytes, an effect blocked by the MC3R antagonist SHU9119. In: Physiology 2010, 30 June - 2 July 2010, University of Manchester.

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2010) Melanocortin peptides modulate pro-inflammatory mediator release from TNF-a stimulated C-20/A4 cells. In: British Orthopaedic Research Society Annual Meeting, 22 - 23 Jun 2009, Newcastle upon Tyne.

Locke, Ian C., White, O.B, Trwoga, P.F. and Afoke, A.N. (2010) The effect of indentor shape on the creep curves of collagen gel. In: OARSI 2010 World Congress on Osteoarthritis, September 23-26, 2010, Brussels, Belgium.

Kaneva, Magdalena, Kerrigan, Mark J.P., Locke, Ian C. and Getting, Stephen J. (2009) Pro-inflammatory mediator release from TNF-? stimulated C-20/A4 cells results in Col II degradation. In: British Orthopaedic Research Society (BORS) Annual Meeting, 22nd - 23rd June 2009, Newcastle.

Shah, Chirag M., Walters, S.E., Locke, Ian C., Chowdrey, Hardial S. and Gordge, Michael P. (2005) Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery into MEG-01 megakaryocytes. In: Ireland-UK Platelet Conference 2005, 04-06 Sep 2005, Dublin, Ireland. (Submitted)

Intekhab-Alam, N.Y., Chowdrey, Hardial S., Knight, R.A. and Locke, Ian C. (2004) A CRH family peptide protects a human chondrocyte cell line against apoptosis. In: OARSI 2004 World Congress on Osteoarthritis, 12/2004, Chicago USA.

Shah, C.M., Locke, Ian C., Chowdrey, Hardial S. and Gordge, Michael P. (2004) Cell surface thiol modification by GSNO: a mechanism of nitric oxide delivery? In: 5th UK Nitric Oxide Forum, 12/2004, Edinburgh, UK. (Submitted)

Petsa, A., Chowdrey, H.S., Knight, R.A., Afoke, A.N. and Locke, Ian C. (2004) Establishment and analysis of 3-D collagen cultures of C-20/A4 chondrocytes. In: OARSI 2004 World Congress on Osteoarthritis, 12/2004, Chicago USA.

Shah, C.M., Locke, Ian C., Chowdrey, H.S. and Gordge, M.P. (2004) Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes. In: Japan-UK Platelet Conference, September 2004, Oxford, UK. (Submitted)

Shah, C.M., Locke, Ian C., Chowdrey, H.S. and Gordge, M.P. (2004) Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes. In: 3rd International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide: 4th Anuual Scientific Meeting of the Nitric Oxide Society of Japan, 24-28 May 2004, Nara, Japan.

Shah, C.M., Locke, Ian C., Chowdrey, Hardial S. and Gordge, Michael P. (2003) Role of protein disulphide isomerase in NO delivery from S-nitrosothiols into megakaryocytes. In: 4th UK Nitric Oxide Forum, December 2003, University of Nottingham, UK. (Submitted)

Petsa, A., Afoke, A.N., Chowdrey, H.S., Knight, R.A., Harris, A.B. and Locke, Ian C. (2003) The behaviour of C-20/A4 chondrocytes in 3-D collagen gel cultures. In: OARSI 2003 World Congress on Osteoarthritis, October 2003, Berlin, Germany.

Prashar, A., Veness, R.G., Locke, Ian C. and Evans, C.S. (2002) Effect of essential oils and their components on cell. In: Future Trends in Phytochemistry, Gargnano, Italy. (Submitted)

Locke, Ian C., Rahman, M.A.A. and Cambridge, G. (1998) A comparison of the variable region genes of two human monoclonal antibodies to myeloperoxidase. In: British Society for Immunology 6th Annual Meeting, 12/1998, Harrogate, UK.

Locke, Ian C., Leaker, B. and Cambridge, G. (1996) Characteristics of anti-myeloperoxidase autoantibodies in vasculitis and other conditions. In: American Society of Nephrology 29th Annual Meeting, 11/1996, New Orleans, USA.

Locke, Ian C., Leaker, B. and Cambridge, G. (1996) Characteristics of antibodies to myeloperoxidase in vasculitic and non-vasculitic conditions. In: American College of Rheumatology 60th National Scientific Meeting , 10/1996, Orlando, USA.

Worral, J.G., Locke, Ian C., Leaker, B., Black, C.M. and Cambridge, G. (1995) Autoantibodies to myeloperoxidase in systemic sclerosis. In: British Society for Rheumatology Heberden Round 1995, 9/1995, Keele University, UK.

Locke, Ian C., Ramsey, M.P., Hill, S.S. and Carpenter, B.G. (1992) Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®. In: IMLS XX Triennial Conference, 9/1992, Liverpool, UK.

Rogers, D.J., Locke, Ian C., Gibbs, R. and Carpenter, B.G. (1990) Purification of the seed lectin from Dolichos biflorus by chromatofocusing. In: 12th International Lectin Conference, 9/1990, University of Davis, USA. (Submitted)

This list was generated on Fri Jun 24 23:21:13 2016 BST.