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Items where Author is Moschos, Sterghios A.

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Number of items: 39.

Brock, G

Brock, Graham J. and Moschos, Sterghios A. and Spivack, Simon D. and Hurteau, Gregory J. (2011) The 3 prime paradigm of the miR-200 family and other microRNAs. Epigenetics, 6 (3). pp. 268-272. ISSN 1559-2294

Cucurull-Sanchez, L

Cucurull-Sanchez, Lourdes and Spink, Karen G. and Moschos, Sterghios A. (2012) Relevance of systems pharmacology in drug discovery. Drug Discovery Today, 17 (13-14). pp. 665-670. ISSN 1359-6446

Denise , H

Denise , Hubert and Moschos, Sterghios A. and Sidders, Ben and Burden, Frances and Perkins, Hannah and Carter, Nikki and Stroud, Tim and Kennedy, Michael and Fancy, Sally A. and Lapthorn, Chris and Lavender, Helen and Kinloch, Ross and Suhy, David A. and Corbau, Romu (2014) Deep sequencing insights in therapeutic shRNA processing and siRNA target cleavage precision. Molecular Therapy Nucleic Acids, 3 . e145. ISSN 2162-2531

Graves, H

Graves, Helen and Taylor, Bruce and Mechiche, Houria and Moschos, Sterghios A. (2010) Flow cytometric identification of cell types in digested mouse lung. In: 9th Annual Symposium on Biopharmaceuticals - San Diego Bio-Pharma Conference, 05 Jun 2010, Hilton San Diego/Del Mar, Del Mar. (Unpublished)

Laxton, C

Laxton, Carl and Brady, Kevin and Moschos, Sterghios A. and Turnpenny, Paul and Rawal, Jaiessh and Pryde, David C. and Sidders, Ben and Corbau, Romu and Pickford, Chris and Murray, E.J. (2011) Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome entry site. Antimicrobial Agents and Chemotherapy, 55 (7). pp. 3105-3114. ISSN 0066-4804

Lazari, O

Lazari, Ovadia and Moschos, Sterghios A. and Kearney, Sarah and Green, M.P. and Spink, Karen G. (2011) Is it in yet? Optimisation and screening of an RNAi delivery screen. In: ELRIG 2011, Spring Meeting. (Unpublished)

Moschos, S

Moschos, Sterghios A. (2010) The role of miRNA in diagnostics. International Drug Discovery, Online only . ISSN 2150-4792

Moschos, Sterghios A. and Spink, Karen G. and Lindsay, Mark A. (2011) Measuring the action of CPP–siRNA conjugates in the lung. Methods in Molecular Biology, 683 (5). pp. 417-429. ISSN 1064-3745

Moschos, Sterghios A. and Spink, Karen G. and Williams, Andrew E. and Lindsay, Mark A. (2008) Targeting the lung using siRNA and antisense based oligonucleotides. Current Pharmaceutical Design, 14 (34). pp. 3620-3627. ISSN 1381-6128

Moschos, Sterghios A. and Jones, Simon W. and Perry, Mark M. and Williams, Andrew E. and Erjefalt, Jonas S. and Turner, John J. and Barnes, Peter J. and Sproat, Brian S. and Gait, Michael J. and Lindsay, Mark A. (2007) Lung delivery studies using siRNA conjugated to TAT(48−60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity. Bioconjugate Chemistry, 18 (5). pp. 1450-1459. ISSN 1043-1802

Moschos, Sterghios A. and Williams, Andrew E. and Perry, Mark M. and Birrell, Mark A. and Belvisi, Maria G. and Lindsay, Mark A. (2007) Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids. BMC Genomics, 8 (1). p. 240. ISSN 1471-2164

Moschos, Sterghios A. and Williams, Andrew E. and Lindsay, Mark A. (2007) Cell-penetrating-peptide-mediated siRNA lung delivery. Biochemical Society. Transactions, 35 (4). pp. 807-810. ISSN 0300-5127

Moschos, Sterghios A. and Bramwell, Vincent W. (2006) Modulating the adjuvanticity of alum by co-administration of muramyl di-peptide (MDP) or Quil-A. Vaccine, 24 (8). pp. 1081-1086. ISSN 0264-410X

Moschos, Sterghios A. and Bramwell, Vincent W. and Somavarapu, Satyanarayna and Alpar, H. Oya (2005) Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation. Vaccine, 23 (16). pp. 1923-1930. ISSN 0264-410X

Moschos, Sterghios A. and Bramwell, Vincent W. and Somavarapu, Satyanarayna and Alpar, H. Oya (2004) Adjuvant synergy: the effects of nasal coadministration of adjuvants. Immunology and Cell Biology, 82 (6). pp. 628-637. ISSN 0818-9641

Moschos, Sterghios A. and Frick, Manfred and Taylor, Bruce and Turnpenny, Paul and Graves, Helen and Spink, Karen G. and Brady, Kevin and Lambiel, David and Collins, David and Rockel, Thomas and Weber, Markus and Lazari, Ovadia and Perez-Tosar, Luis and Fancy, Sally A. and Lapthorn, Chris and Green, Martin X. and Evans, Steve and Selby, Matthew and Jones, Gareth and Jones, Lyn and Kearney, Sarah and Mechiche, Houria and Gikunju, Diana and Subramanian, Romesh and Uhlmann, Eugen and Jurk, Marion and Vollmer, Jörg and Ciaramella, Giuseppi and Yeadon, Michael (2011) Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense. Molecular Therapy, 19 (12). pp. 2163-2168. ISSN 1525-0016

Moschos, Sterghios A. and Perry, Mark M. and Williams, Andrew E. and Lindsay, Mark A. (2007) Expression profiling implicates microRNA expression in the resolution of the inflammatory response in vivo. In: Proceedings of the American Thoracic Society 2007 International Conference, 18 - 23 May 2007, San Francisco.

Moschos, Sterghios A. and Pandit, Sreenivas and Somavarapu, Satyanarayna and Balaban, N. and Alpar, H. Oya (2004) New strategies in vaccine research: targeting quorum sensing pathways for prophylaxis against antibiotic-resistant S. aureus infections. In: Proceedings of the 31st International Symposium for the Controlled Release of Bioactive Materials 2004, 12 - 16 Jun 2004, Honolulu, USA.

Moschos, Sterghios A. and Bramwell, Vincent W. and Alpar, H. Oya (2003) Considerations in the antigen-stimulated, primed, primary splenocyte culture model as an in vitro vaccine screening tool. In: Proceedings of the 30th International Symposium for the Controlled Release of Bioactive Materials, 19 - 23 Jul 2003, Glasgow.

Moschos, Sterghios A. and Somavarapu, Satyanarayna and Bramwell, Vincent W. and Randall, L. and Guy, B. and Alpar, H. Oya (2001) Quil-A and MDP enhances the adjuvanticity of alum for intramuscular delivery of rURE. Immunology, 104 (s1). p. 98. ISSN 0019-2805

Moschos, Sterghios A. and Somavarapu, Satyanarayna and Eyles, James E. and McHugh, C. and Bramwell, Vincent W. and Randall, L. and Guy, B. and Alpar, H. Oya (2001) Evaluation of adjuvanted recombinant urease for effective immunization against Helicobacter pylori. Immunology, 104 (s1). p. 98. ISSN 0019-2805

Moschos, Sterghios A. and Somavarapu, Satyanarayna and Eyles, James E. and McHugh, C. and Bramwell, Vincent W. and Randall, L. and Guy, B. and Alpar, H. Oya (2001) Immunogenicity of adjuvanted recombinant urease administered intra-muscularly. In: Proceedings of the 28th International Symposium for the Controlled Release of Bioactive Materials, 23 - 27 Jun 2001, San Diego, USA.

Moschos, Sterghios A. and Somavarapu, Satyanarayna and Singh, Jasvinder and Bramwell, Vincent W. and Randall, L. and Guy, B. and Alpar, H. Oya (2001) Immunogenicity of adjuvanted recombinant urease administered intranasally. In: Proceedings of the 28th International Symposium for the Controlled Release of Bioactive Materials, 23 - 27 Jun 2001, San Diego, USA.

Moschos, Sterghios A. and Somavarapu, Satyanarayna and Singh, Jasvinder and Bramwell, Vincent W. and Randall, L. and Guy, B. and Alpar, H. Oya (2000) Novel protein secretion from both ex-vivo Peyers’ patches and in-vivo; induction by microsphere encapsulated diphtheria toxoid. In: Proceedings of the 27th International Symposium for the Controlled Release of Bioactive Materials, 09 - 13 Jul 2001, Paris, France.

Moschos, Sterghios A. (2012) In vivo pharmacology: reaping the benefits of analysis at the cell type level. Pharmacology Matters Newsletter, 5 (1). pp. 15-16. ISSN 1757-8175

Moschos, Sterghios A. (2003) Double identity. New Scientist, 2424 . ISSN 0262-4079

Moschos, Sterghios A. (2012) Genomic biomarkers for patient selection and stratification: the cancer paradigm. Bioanalysis, 4 (20). pp. 2499-2511. ISSN 1757-6180

Moschos, Sterghios A. (2013) MicroRNA biotherapeutics: key challenges from a drug development perspective. In: Jones, Lyn and McKnight, Andrew, (eds.) Biotherapeutics: recent developments using chemical and molecular biology. RSC Drug Discovery Series (36). The Royal Society of Chemistry, London, pp. 176-223. ISBN 9781849736015

Perry, M

Perry, Mark M. and Moschos, Sterghios A. and Williams, Andrew E. and Shepherd, Neil J. and Larner-Svensson, Hanna M. and Lindsay, Mark A. (2008) Rapid changes in microRNA-146a expression negatively regulate the IL-1β-induced inflammatory response in human lung alveolar epithelial cells. Journal of Immunology, 180 (8). pp. 5689-5698. ISSN 0022-1767

Perry, Mark M. and Moschos, Sterghios A. and Williams, Andrew E. and Lindsay, Mark A. (2007) ncreased expression of microRNA-146a/b negatively regulates IL-1b induced cytokine release from airway epithelial cells. In: Proceedings of the American Thoracic Society 2007 International Conference, 18 - 23 May 2007, San Francisco.

Suhy, D

Suhy, David A. and Kao, Shih-Chu and Mao, Tin and Whiteley, Laurence and Denise, Hubert and Souberbielle, Bernard and Burdick, Andrew D. and Hayes, Kyle and Wright, J. Fraser and Lavender, Helen and Roelvink, Peter and Kolykhalov, Alexander and Brady, Kevin and Moschos, Sterghios A. and Hauck, Bernd and Zelenaia, Olga and Zhou, Shangzhen and Scribner, Curt and High, Katherine A. and Renison, Sara H. and Corbau, Romu (2012) Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate model. Molecular Therapy, 20 (9). pp. 1737-1749. ISSN 1525-0016

Tsitsiou, E

Tsitsiou, Eleni and Williams, Andrew E. and Moschos, Sterghios A. and Patel, Ketan and Rossios, Christos and Jiang, Xiaoying and Adams, Oona-Delpuech and Macedo, Patricia and Booton, Richard and Gibeon, David and Chung, Kian Fan and Lindsay, Mark A. (2012) Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma. Journal of Allergy and Clinical Immunology, 129 (1). pp. 95-103. ISSN 0091-6749

Turner, J

Turner, John J. and Jones, Simon W. and Moschos, Sterghios A. and Lindsay, Mark A. and Gait, Michael J. (2007) MALDI-TOF mass spectral analysis of siRNA degradation in serum confirms an RNAse A-like activity. Molecular BioSystems, 3 (1). pp. 43-50. ISSN 1742-206X

Turner, John J. and Fabani, M.M. and Jones, Simon W. and Moschos, Sterghios A. and Perry, Mark M. and Lindsay, Mark A. and Gait, Michael J. (2006) In vitro and in vivo delivery studies of siRNA-peptide conjugates. Journal of RNAi and Gene Silencing, 2 (2). pp. 171-172. ISSN 1747-0854

Turner, John J. and Somavarapu, Satyanarayna and Moschos, Sterghios A. and Randall, L. and Simpkin, G. and Alpar, H. Oya (2000) Microsphere encapsulated Diphtheria Toxoid induces protein secretion from in-vitro Peyers’ patches and in vivo. In: Proceedings of the 3rd World Meeting APV/APGI 2000, 3 - 6 Apr 2000, Berlin, Germany.

Williams, A

Williams, Andrew E. and Perry, Mark M. and Moschos, Sterghios A. and Larner-Svensson, Hanna M. and Lindsay, Mark A. (2008) Role of miRNA-146a in the regulation of the innate immune response and cancer. Biochemical Society. Transactions, 36 (6). pp. 1211-1215. ISSN 0300-5127

Williams, Andrew E. and Perry, Mark M. and Moschos, Sterghios A. and Lindsay, Mark A. (2007) microRNA expression in the aging mouse lung. BMC Genomics, 8 (1). p. 172. ISSN 1471-2164

Williams, Andrew E. and Moschos, Sterghios A. and Perry, Mark M. and Barnes, Peter J. and Lindsay, Mark A. (2007) Maternally imprinted microRNAs are differentially expressed during mouse and human lung development. Developmental Dynamics, 236 (2). pp. 572-580. ISSN 1058-8388

Williams, Andrew E. and Moschos, Sterghios A. and Perry, Mark M. and Lindsay, Mark A. (2007) MicroRNAs are differentially expressed in the developing lung but not in the aged lung. In: Proceedings of the American Thoracic Society 2007 International Conference, 18 - 23 May 2007, San Francisco.

This list was generated on Wed Nov 26 07:10:07 2014 GMT.