Items where Author is Perretti, Mauro

2014

Locatelli, Irene and Sutti, Salvatore and Jindal, Aastha and Vacchiano, Marco and Bozzola, Cristina and Reutelingsperger, Chris and Kusters, Dennis and Bena, Stefania and Parola, Maurizio and Paternostro, Claudia and Bugianesi, Elisabetta and McArthur, Simon and Albano, Emanuele and Perretti, Mauro (2014) Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. Hepatology, 60 (2). pp. 531-544. ISSN 1527-3350

Gobbetti, Thomas and Coldewey, Sina M. and Chen, Jianmin and McArthur, Simon and le Faouder, Pauline and Cenac, Nicolas and Flower, Roderick J. and Thiemermann, Christoph and Perretti, Mauro (2014) Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of the National Academy of Sciences of the United States of America, 111 (52). pp. 18685-18690. ISSN 0027-8424

2013

Fowkes, Robert C. and Moradi-Bidhendi, Niloufar and Branceleone, Vincenzo and Gulrez Zariwala, M. and Brady, Daniel and Jessop, David S. and Perretti, Mauro and Renshaw, Derek (2013) Annexin-A1 protein and its relationship to cortisol in human saliva. Psychoneuroendocrinology, 38 (5). pp. 722-727. ISSN 0306-4530

Kosicka, Anna and Cunliffe, Adam and Mackenzie, Richard W.A. and Gulrez Zariwala, M. and Perretti, Mauro and Flower, Roderick J. and Renshaw, Derek (2013) Attenuation of plasma annexin A1 in human obesity. FASEB Journal, 27 (1). pp. 368-378. ISSN 0892-6638

Cooray, Sadani N. and Gobbetti, Thomas and Montero-Melendez, Trinidad and McArthur, Simon and Thompson, Dawn and Clark, Adrian J.L. and Flower, Roderick J. and Perretti, Mauro (2013) Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proceedings of the National Academy of Sciences of the United States of America, 110 (45). pp. 18232-18237. ISSN 1091-6490

Cash, Jenna L. and Bena, Stefania and Headland, Sarah E. and McArthur, Simon and Brancaleone, Vincenzo and Perretti, Mauro (2013) Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO reports, 14 (11). pp. 999-1007. ISSN 1469-3178

2012

Dalli, Jesmond and Montero-Melendez, Trinidad and McArthur, Simon and Perretti, Mauro (2012) Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Frontiers in pharmacology, 3 . p. 28. ISSN 1663-9812

2011

Dowejko, M.M and Smith, Caroline L. and Getting, Stephen J. and Perretti, Mauro and Le Tissier, Paul and Murray, Joanne F. (2011) Comparison between the total pituitary hormone content in wild type and melanocortin 3 receptor (MC3) null male and female mice. In: Society for Reproduction and Fertility, 11th - 13th July 2011, Brighton.

Dowejko, M.M and Smith, Caroline L. and Getting, Stephen J. and Perretti, Mauro and Le Tissier, Paul and Murray, Joanne F. (2011) Total pituitary hormone content in wild type and MC3 null male and female mice. In: British Society for Neuroendocrinology, 3rd - 5th July 2011, Cambridge.

2010

Leoni, Giovanna and Voisin, M-B. and Carlson, K. and Getting, Stephen J. and Nourshargh, S. and Perretti, Mauro (2010) The melanocortin MC1 receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. British Journal of Pharmacology, 160 (1). pp. 171-180. ISSN 0007-1188

Yazid, Samia and Leoni , Giovanna and Getting, Stephen J. and Cooper, Dianne and Solito, Egle and Perretti, Mauro and Flower, Roderick J. (2010) Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via Annexin-A1 mobilization. Arteriosclerosis, Thrombosis, and Vascular Biology, 30 (9). pp. 1718-1724. ISSN 1079-5642

Patel, Hetal B. and Bombardieri, Michele and Sampaio, André L.F. and D'Acquisto, Fulvio and Gray, Mohini and Grieco, Paolo and Getting, Stephen J. and Pitzalis, Costantino and Perretti, Mauro (2010) Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis. FASEB Journal, 24 (12). pp. 4835-4843. ISSN 0892-6638

Renshaw, Derek and Montero-Melendez, Trinidad and Dalli, Jesmond and Kamal, Ahmad and Brancaleone, Vincenzo and D'Acquisto, Fulvio and Cirino, Giuseppe and Perretti, Mauro (2010) Downstream gene activation of the receptor ALX by the agonist Annexin A1. PLoS ONE, 5 (9). e12771. ISSN 1932-6203

2009

Tripatara, Pinpat and Patel, Nimesh S.A. and Brancaleone, Vincenzo and Renshaw, Derek and Rocha, Joao and Sepodes, Bruno and Mota-Filipe, Helder and Perretti, Mauro and Thiemermann, Christoph (2009) Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. European Journal of Pharmacology, 606 (1-3). pp. 205-209. ISSN 0014-2999

2008

Leoni , Giovanna and Patel, Hetal B. and Sampaio, André L.F. and Gavins, Felicity N.E. and Murray, Joanne F. and Grieco, Paolo and Getting, Stephen J. and Perretti, Mauro (2008) Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB Journal, 22 (12). pp. 4228-4238. ISSN 0892-6638

Getting, Stephen J. and Riffo-Vasquez, Yanira and Pitchford, Simon and Kaneva, Magdalena and Grieco, Paolo and Page, Clive P. and Perretti, Mauro and Spina, Domenico (2008) A role for MC3R in modulating lung inflammation. Pulmonary Pharmacology and Therapeutics, 21 (6). pp. 866-873. ISSN 1094-5539

Dalli, Jesmond and Norling, Lucy V. and Renshaw, Derek and Cooper, Dianne and Leung, Kit-Yi and Perretti, Mauro (2008) Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. Blood, 112 (6). pp. 2512-2519. ISSN 0006-4971

Wotherspoon, Glen and Yogarajah, S. and Lynch, S. and Smith, Caroline L. and Getting, Stephen J. and Perretti, Mauro and Murray, Joanne F. (2008) Melanocortin 3 receptor in the testes of mice. pA2 Online. From the University of Brighton, Winter 2008 Meeting: Proceedings of the British Pharmacological Society, 6 (4). P008. ISSN 1741-1157

Yogarajah, S. and Lynch, S. and Smith, Caroline L. and Getting, Stephen J. and Perretti, Mauro and Murray, Joanne F. (2008) Melanocortin 3 receptor in the testes of mice. In: Society for Reproduction and Fertility, 29 Jun - 01 Jul 2008, Edinburgh.

Leoni , Giovanna and Patel, Hetal B. and Sampaio, André L.F. and Gavins, Felicity N.E. and Getting, Stephen J. and Perretti, Mauro (2008) Tonic inhibitory control of the mesenteric microcirculation by the melanocortin type 3 receptor. Journal of Vascular Research, 45 (Suppl2). ISSN 1018-1172

Leoni , Giovanna and Patel, Hetal B. and Sampaio, André L.F. and Gavins, Felicity N.E. and Getting, Stephen J. and Perretti, Mauro (2008) Inhibitory role of endogenous melanocortin type 3 receptor in the inflamed microcirculation. In: William Harvey Day, 14th October 2008 , St. Barts Hospital, London.

2007

Renshaw, Derek and Urquhart, P. and Perretti, Mauro (2007) Therapeutic exploitation of endogenous anti-inflammatory mechanisms: old and new leads. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 5 (4). pp. 289-305. ISSN 1871-5230

Leoni , Giovanna and Getting, Stephen J. and Gavins, Felicity N.E. and Perretti, Mauro (2007) Crucial role for endogenous melanocortin type 3 receptor in mesenteric post-reperfusion injury. PC106. In: Life Sciences, 8th - 12th July 2007, Glasgow.

Patel, Hetal B. and Sampaio, André L.F. and Getting, Stephen J. and Gray, M. and Perretti, Mauro (2007) Endogenous MC3R and inhibition of inflammatory arthritis. PC112. In: Life Sciences, 8th - 12th July 2007, Glasgow.

2006

Lam, Connie W. and Perretti, Mauro and Getting, Stephen J. (2006) Melanocortin receptor signaling in RAW264.7 macrophage cell line. Peptides, 27 (2). pp. 404-412. ISSN 0196-9781

Getting, Stephen J. and Di Filippo, Clara and D'Amico, Michele and Perretti, Mauro (2006) The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage. European Journal of Pharmacology, 532 (1-2). pp. 138-144. ISSN 0014-2999

Getting, Stephen J. and Lam, Connie W. and Chen, Airu S. and Grieco, Paolo and Perretti, Mauro (2006) Melanocortin 3 receptors control crystal-induced inflammation. FASEB Journal, 20 (13). pp. 2234-2241. ISSN 0892-6638

Getting, Stephen J. and Lam, Connie W. and Leoni , Giovanna and Gavins, Felicity N.E. and Grieco, Paolo and Perretti, Mauro (2006) [D -Trp8]-γ -melanocyte -stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1 R(Recessive Yellow e/e Mouse). Molecular Pharmacology, 70 (6). pp. 1850-1855. ISSN 0026-895X

2005

Lam, Connie W. and Getting, Stephen J. and Perretti, Mauro (2005) In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation. Journal of Immunology, 174 (4). pp. 2297-2304. ISSN 0022-1767

2004

Getting, Stephen J. and Di Filippo, Clara and Christian, Helen C. and Lam, Connie W. and Rossi, Francesco and D'Amico, Michele and Perretti, Mauro (2004) MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct. Journal of Leukocyte Biology, 76 (4). pp. 845-853. ISSN 0741-5400

Wells, D. and Wells, K. and Liu, K. and Hannon, Robert and Croxtall, Jamie D. and Damazo, A.S. and Oliani, Sonia M. and Getting, Stephen J. and Parente, Luca and Paul-Clark, Mark and Yona, Simon and Gavins, Felicity N.E. and Martin, Joanne and Christian, Helen C. and Cover, Patricia O. and John, C.D. and Solito, Egle and Morris, John F. and Perretti, Mauro and Buckingham, Julia C. and Flower, Roderick J. (2004) The annexin 1-/- mouse: phenotypic studies. Annexins, 1 (2). pp. 109-120. ISSN 1547-6294

Lam, Connie W. and Getting, Stephen J. and Perretti, Mauro (2004) Activation of melanocortin receptors induces cAMP-dependent hemeoxygenase-1 expression in murine macrophages. pA2 Online. Winter 2004 Meeting: Proceedings of the British Pharmacological Society . 059P. ISSN 1741-1157

2003

Getting, Stephen J. and Christian, Helen C. and Lam, Connie W. and Gavins, Felicity N.E. and Flower, Roderick J. and Schiöth, Helgi B. and Perretti, Mauro (2003) Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. Journal of Immunology, 170 (6). pp. 3323-3330. ISSN 0022-1767

Getting, Stephen J. and Schiöth, Helgi B. and Perretti, Mauro (2003) Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides. Journal of Pharmacology and Experimental Therapeutics, 306 (2). pp. 631-637. ISSN 0022-3565

Perretti, Mauro and Getting, Stephen J. (2003) Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo. Methods in Molecular Biology, 225 . pp. 139-146. ISSN 1064-3745

Hannon, Robert and Croxtall, Jamie D. and Getting, Stephen J. and Roviezzo, Fiorentina and Yona, Simon and Paul-Clark, Mark and Gavins, Felicity N.E. and Perretti, Mauro and Morris, John F. and Buckingham, Julia C. and Flower, Roderick J. (2003) Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB Journal, 17 (2). pp. 253-255. ISSN 0892-6638

Perretti, Mauro and Getting, Stephen J. (2003) Migration of specific leukocyte sub-sets in response to cytokine or chemokine application in vivo. In: Winyard, Paul G. and Willoughby, D.A., (eds.) Inflammation Protocols. Humana Press, Totowa, NJ, pp. 139-146. ISBN 9780896039704

2002

Perretti, Mauro and Chiang, Nan and La, Mylinh and Fierro, Iolanda M. and Marullo, Stefano and Getting, Stephen J. and Solito, Egle and Serhan, Charles N. (2002) Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nature Medicine, 8 (11). pp. 1296-1302. ISSN 1078-8956

Getting, Stephen J. and Christian, Helen C. and Flower, Roderick J. and Perretti, Mauro (2002) Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis & Rheumatism, 46 (10). pp. 2765-2775. ISSN 0004-3591

Getting, Stephen J. and Mahoney, David J. and Cao, Thong V. and Rugg, Marilyn S. and Fries, Erik and Milner, Caroline M. and Perretti, Mauro and Day , Anthony J. (2002) The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner. Journal of Biological Chemistry, 277 (52). pp. 51068-51076. ISSN 0021-9258

Malcangio, Marzia and Getting, Stephen J. and Grist, John and Cunningham, Joanna R. and Bradbury, Elizabeth J. and Issa, Peter Charbel and Lever, Isobel J. and Pezet, Sophie and Perretti, Mauro (2002) A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. FASEB Journal, 16 (7). pp. 730-732. ISSN 0892-6638

Roviezzo, Fiorentina and Getting, Stephen J. and Paul-Clark, Mark and Yona, Simon and Gavins, Felicity N.E. and Perretti, Mauro and Hannon, Robert and Croxtall, Jamie D. and Buckingham, Julia C. and Flower, Roderick J. (2002) The annexin-1 knockout mouse: what it tells us about the inflammatory response. Journal of Physiology and Pharmacology, 53 (4, part 1). 541 -553. ISSN 0867-5910

Carollo, M. and Getting, Stephen J. and Delaney, S. and Christie, M.I. and Perretti, Mauro (2002) Characterization of CXC and CC chemokine expression in a murine model of chronic granuloma. Inflammation Research, 51 (2). pp. 110-111. ISSN 1023-3830

2001

Getting, Stephen J. and Allcock, Graham H. and Flower, Roderick J. and Perretti, Mauro (2001) Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties. Journal of Leukocyte Biology, 69 (1). pp. 98-104. ISSN 0741-5400

Perretti, Mauro and Getting, Stephen J. and Solito, Egle and Murphy, Philip M. and Gao, Ji-Liang (2001) Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. American Journal of Pathology, 158 (6). pp. 1969-1973. ISSN 0002-9440

Getting, Stephen J. and Perretti, Mauro (2001) Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics. Current opinion in investigational drugs, 2 (8). pp. 1064-1069. ISSN 1472-4472

Mabley, J.G. and Jagtap, P. and Perretti, Mauro and Getting, Stephen J. and Salzman, Andrew L. and Virag, L. and Szabo, E. and Soriano, F.G. and Liaudet, L. and Hasko, G. and Marton, A. and Southan, G.J. and Abdelkarim, G.E. and Szabo, Csaba (2001) Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase. Inflammation Research, 50 (11). pp. 561-569. ISSN 1023-3830

2000

Getting, Stephen J. and Perretti, Mauro (2000) MC3-R as a novel target for anti-inflammatory therapy. Drug News & Perspectives, 13 (1). pp. 19-27. ISSN 0214-0934

1999

Getting, Stephen J. and Gibbs, Linda and Clark, Adrian J.L. and Flower, Roderick J. and Perretti, Mauro (1999) POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. Journal of Immunology, 162 (12). pp. 7446-7453. ISSN 0022-1767

1998

Roderick J. Flower, Stephen J. Getting, Mauro Perretti (1998) Compounds for use in the treatment of inflammation. UK patent no. 9816234.0, 24th July 1998. PCT/GB99/02392, 22nd July 1999..

1997

Tailor, Anitaben and Das, Anuk M. and Getting, Stephen J. and Flower, Roderick J. and Perretti, Mauro (1997) Sub-acute treatment of rats with dexamethasone reduces ICAM-1 levels on circulating monocytes. Biochemical and Biophysical Research Communications, 231 (3). pp. 675-678. ISSN 0006-291X

Getting, Stephen J. and Flower, Roderick J. and Perretti, Mauro (1997) Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. British Journal of Pharmacology, 120 (6). pp. 1075-1082. ISSN 0007-1188

Szabo, Csaba and Lim, Lina H.K. and Cuzzocrea, Salvatore and Getting, Stephen J. and Zingarelli, Basilia and Flower, Roderick J. and Salzman, Andrew L. and Perretti, Mauro (1997) Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts anti-inflammatory effects. Journal of experimental medicine, 186 (7). pp. 1041-1049. ISSN 0022-1007

Getting, Stephen J. and Flower, Roderick J. and Parente, Luca and de Medicis, Rinaldo and Lussier, Andre and Woliztky, Barry A. and Martins, Marco A. and Perretti, Mauro (1997) Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. Journal of Pharmacology and Experimental Therapeutics, 283 (1). pp. 123-130. ISSN 0022-3565